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Role of Integrins in Resistance to Therapies Targeting Growth Factor Receptors in Cancer
Integrins contribute to cancer progression and aggressiveness by activating intracellular signal transduction pathways and transducing mechanical tension forces. Remarkably, these adhesion receptors share common signaling networks with receptor tyrosine kinases (RTKs) and support their oncogenic act...
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| Publicado no: | Cancers (Basel) |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6562376/ https://ncbi.nlm.nih.gov/pubmed/31109009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11050692 |
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