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β1 Integrins as Therapeutic Targets to Disrupt Hallmarks of Cancer
Integrins belong to a large family of αβ heterodimeric transmembrane proteins first recognized as adhesion molecules that bind to dedicated elements of the extracellular matrix and also to other surrounding cells. As important sensors of the cell microenvironment, they regulate numerous signaling pa...
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| Veröffentlicht in: | Front Pharmacol |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4656837/ https://ncbi.nlm.nih.gov/pubmed/26635609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00279 |
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