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Selection of Nucleic Acid Aptamers Targeting Tumor Cell-Surface Protein Biomarkers

Aptamers are nucleic acids referred to as chemical antibodies as they bind to their specific targets with high affinity and selectivity. They are selected via an iterative process known as ‘selective evolution of ligands by exponential enrichment’ (SELEX). Aptamers have been developed against numero...

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Détails bibliographiques
Publié dans:Cancers (Basel)
Auteurs principaux: Mercier, Marie-Cécile, Dontenwill, Monique, Choulier, Laurence
Format: Artigo
Langue:Inglês
Publié: MDPI 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483888/
https://ncbi.nlm.nih.gov/pubmed/28635657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers9060069
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