IgE re-programs alternatively-activated human macrophages towards pro-inflammatory anti-tumoural states

BACKGROUND: Antibody Fc-driven engagement of macrophages is critical for evoking cellular activation and effector functions and influencing tumour-associated macrophage (TAM) recruitment. We previously reported that IgE class antibodies promote restriction of cancer growth in rodent models associate...

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Vydáno v:EBioMedicine
Hlavní autoři: Pellizzari, Giulia, Hoskin, Coran, Crescioli, Silvia, Mele, Silvia, Gotovina, Jelena, Chiaruttini, Giulia, Bianchini, Rodolfo, Ilieva, Kristina, Bax, Heather J., Papa, Sophie, Lacy, Katie E., Jensen-Jarolim, Erika, Tsoka, Sophia, Josephs, Debra H., Spicer, James F., Karagiannis, Sophia N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
Témata:
Research paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562024/
https://ncbi.nlm.nih.gov/pubmed/30956175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.03.080
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