Feedback inhibition of cAMP effector signaling by a chaperone-assisted ubiquitin system

Activation of G-protein coupled receptors elevates cAMP levels promoting dissociation of protein kinase A (PKA) holoenzymes and release of catalytic subunits (PKAc). This results in PKAc-mediated phosphorylation of compartmentalized substrates that control central aspects of cell physiology. The mec...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Rinaldi, Laura, Delle Donne, Rossella, Catalanotti, Bruno, Torres-Quesada, Omar, Enzler, Florian, Moraca, Federica, Nisticò, Robert, Chiuso, Francesco, Piccinin, Sonia, Bachmann, Verena, Lindner, Herbert H, Garbi, Corrado, Scorziello, Antonella, Russo, Nicola Antonino, Synofzik, Matthis, Stelzl, Ulrich, Annunziato, Lucio, Stefan, Eduard, Feliciello, Antonio
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561907/
https://ncbi.nlm.nih.gov/pubmed/31189917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10037-y
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki