Mitochondrial AKAP121 Links cAMP and src Signaling to Oxidative Metabolism

AKAP121 focuses distinct signaling events from membrane to mitochondria by binding and targeting cAMP-dependent protein kinase (PKA), protein tyrosine phosphatase (PTPD1), and mRNA. We find that AKAP121 also targets src tyrosine kinase to mitochondria via PTPD1. AKAP121 increased src-dependent phosp...

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Main Authors: Livigni, Alessandra, Scorziello, Antonella, Agnese, Savina, Adornetto, Annagrazia, Carlucci, Annalisa, Garbi, Corrado, Castaldo, Imma, Annunziato, Lucio, Avvedimento, Enrico V., Feliciello, Antonio
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1345664/
https://ncbi.nlm.nih.gov/pubmed/16251349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-09-0827
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