Scalable optimal Bayesian classification of single-cell trajectories under regulatory model uncertainty

BACKGROUND: Single-cell gene expression measurements offer opportunities in deriving mechanistic understanding of complex diseases, including cancer. However, due to the complex regulatory machinery of the cell, gene regulatory network (GRN) model inference based on such data still manifests signifi...

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Vydáno v:BMC Genomics
Hlavní autoři: Hajiramezanali, Ehsan, Imani, Mahdi, Braga-Neto, Ulisses, Qian, Xiaoning, Dougherty, Edward R.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561847/
https://ncbi.nlm.nih.gov/pubmed/31189480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-5720-3
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