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Scalable optimal Bayesian classification of single-cell trajectories under regulatory model uncertainty

BACKGROUND: Single-cell gene expression measurements offer opportunities in deriving mechanistic understanding of complex diseases, including cancer. However, due to the complex regulatory machinery of the cell, gene regulatory network (GRN) model inference based on such data still manifests signifi...

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Bibliografske podrobnosti
izdano v:BMC Genomics
Main Authors: Hajiramezanali, Ehsan, Imani, Mahdi, Braga-Neto, Ulisses, Qian, Xiaoning, Dougherty, Edward R.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561847/
https://ncbi.nlm.nih.gov/pubmed/31189480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-5720-3
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