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Implication of DNA repair genes in Lynch-like syndrome
Many colorectal cancers (CRCs) that exhibit microsatellite instability (MSI) are not explained by MLH1 promoter methylation or germline mutations in mismatch repair (MMR) genes, which cause Lynch syndrome (LS). Instead, these Lynch-like syndrome (LLS) patients have somatic mutations in MMR genes. Ho...
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| Yayımlandı: | Fam Cancer |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6561810/ https://ncbi.nlm.nih.gov/pubmed/30989425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-019-00128-6 |
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