Implication of DNA repair genes in Lynch-like syndrome

Many colorectal cancers (CRCs) that exhibit microsatellite instability (MSI) are not explained by MLH1 promoter methylation or germline mutations in mismatch repair (MMR) genes, which cause Lynch syndrome (LS). Instead, these Lynch-like syndrome (LLS) patients have somatic mutations in MMR genes. Ho...

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I publikationen:Fam Cancer
Huvudupphovsmän: Xicola, Rosa M, Clark, Julia R, Carroll, Timothy, Alvikas, Jurgis, Marwaha, Priti, Regan, Maureen R, Lopez-Giraldez, Francesc, Choi, Jungmin, Emmadi, Rajyasree, Alagiozian-Angelova, Victoria, Kupfer, Sonia S., Ellis, Nathan A, Llor, Xavier
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561810/
https://ncbi.nlm.nih.gov/pubmed/30989425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-019-00128-6
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