Enrichment of inflammatory bowel disease and colorectal cancer risk variants in colon expression quantitative trait loci

BACKGROUND: Genome-wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) associated with diseases of the colon including inflammatory bowel diseases (IBD) and colorectal cancer (CRC). However, the functional role of many of these SNPs is largely unknown and tissue-sp...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Hulur, Imge, Gamazon, Eric R, Skol, Andrew D, Xicola, Rosa M, Llor, Xavier, Onel, Kenan, Ellis, Nathan A, Kupfer, Sonia S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351699/
https://ncbi.nlm.nih.gov/pubmed/25766683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1292-z
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