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Enrichment of inflammatory bowel disease and colorectal cancer risk variants in colon expression quantitative trait loci

BACKGROUND: Genome-wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) associated with diseases of the colon including inflammatory bowel diseases (IBD) and colorectal cancer (CRC). However, the functional role of many of these SNPs is largely unknown and tissue-sp...

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Bibliographische Detailangaben
Veröffentlicht in:BMC Genomics
Hauptverfasser: Hulur, Imge, Gamazon, Eric R, Skol, Andrew D, Xicola, Rosa M, Llor, Xavier, Onel, Kenan, Ellis, Nathan A, Kupfer, Sonia S
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351699/
https://ncbi.nlm.nih.gov/pubmed/25766683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1292-z
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