Implication of DNA repair genes in Lynch-like syndrome

Many colorectal cancers (CRCs) that exhibit microsatellite instability (MSI) are not explained by MLH1 promoter methylation or germline mutations in mismatch repair (MMR) genes, which cause Lynch syndrome (LS). Instead, these Lynch-like syndrome (LLS) patients have somatic mutations in MMR genes. Ho...

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Detalhes bibliográficos
Publicado no:Fam Cancer
Main Authors: Xicola, Rosa M, Clark, Julia R, Carroll, Timothy, Alvikas, Jurgis, Marwaha, Priti, Regan, Maureen R, Lopez-Giraldez, Francesc, Choi, Jungmin, Emmadi, Rajyasree, Alagiozian-Angelova, Victoria, Kupfer, Sonia S., Ellis, Nathan A, Llor, Xavier
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561810/
https://ncbi.nlm.nih.gov/pubmed/30989425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-019-00128-6
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