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Evolution of protein interfaces in multimers and fibrils

A majority of cellular proteins function as part of multimeric complexes of two or more subunits. Multimer formation requires interactions between protein surfaces that lead to closed structures, such as dimers and tetramers. If proteins interact in an open-ended way, uncontrolled growth of fibrils...

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Bibliografiska uppgifter
I publikationen:J Chem Phys
Huvudupphovsmän: Zabel, W. Jeffrey, Hagner, Kyle P., Livesey, Benjamin J., Marsh, Joseph A., Setayeshgar, Sima, Lynch, Michael, Higgs, Paul G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: AIP Publishing LLC 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561775/
https://ncbi.nlm.nih.gov/pubmed/31202237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.5086042
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