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Evolution of protein interfaces in multimers and fibrils

A majority of cellular proteins function as part of multimeric complexes of two or more subunits. Multimer formation requires interactions between protein surfaces that lead to closed structures, such as dimers and tetramers. If proteins interact in an open-ended way, uncontrolled growth of fibrils...

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Bibliografiske detaljer
Udgivet i:J Chem Phys
Main Authors: Zabel, W. Jeffrey, Hagner, Kyle P., Livesey, Benjamin J., Marsh, Joseph A., Setayeshgar, Sima, Lynch, Michael, Higgs, Paul G.
Format: Artigo
Sprog:Inglês
Udgivet: AIP Publishing LLC 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561775/
https://ncbi.nlm.nih.gov/pubmed/31202237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.5086042
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