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Evolution of protein interfaces in multimers and fibrils

A majority of cellular proteins function as part of multimeric complexes of two or more subunits. Multimer formation requires interactions between protein surfaces that lead to closed structures, such as dimers and tetramers. If proteins interact in an open-ended way, uncontrolled growth of fibrils...

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Detalhes bibliográficos
Publicado no:J Chem Phys
Main Authors: Zabel, W. Jeffrey, Hagner, Kyle P., Livesey, Benjamin J., Marsh, Joseph A., Setayeshgar, Sima, Lynch, Michael, Higgs, Paul G.
Formato: Artigo
Idioma:Inglês
Publicado em: AIP Publishing LLC 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561775/
https://ncbi.nlm.nih.gov/pubmed/31202237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.5086042
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