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Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression

The Polycomb system modifies chromatin and plays an essential role in repressing gene expression to control normal mammalian development. However, the components and mechanisms that define how Polycomb protein complexes achieve this remain enigmatic. Here, we use combinatorial genetic perturbation c...

詳細記述

保存先:
書誌詳細
出版年:Mol Cell
主要な著者: Fursova, Nadezda A., Blackledge, Neil P., Nakayama, Manabu, Ito, Shinsuke, Koseki, Yoko, Farcas, Anca M., King, Hamish W., Koseki, Haruhiko, Klose, Robert J.
フォーマット: Artigo
言語:Inglês
出版事項: Cell Press 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561741/
https://ncbi.nlm.nih.gov/pubmed/31029541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.03.024
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