Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition

RNA-binding proteins (RBPs) and long non-coding RNAs (lncRNAs) are key regulators of gene expression, but their joint functions in coordinating cell fate decisions are poorly understood. Here we show that the expression and activity of the RBP TDP-43 and the long isoform of the lncRNA Neat1, the sca...

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Pubblicato in:Mol Cell
Autori principali: Modic, Miha, Grosch, Markus, Rot, Gregor, Schirge, Silvia, Lepko, Tjasa, Yamazaki, Tomohiro, Lee, Flora C.Y., Rusha, Ejona, Shaposhnikov, Dmitry, Palo, Michael, Merl-Pham, Juliane, Cacchiarelli, Davide, Rogelj, Boris, Hauck, Stefanie M., von Mering, Christian, Meissner, Alexander, Lickert, Heiko, Hirose, Tetsuro, Ule, Jernej, Drukker, Micha
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561722/
https://ncbi.nlm.nih.gov/pubmed/31047794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.03.041
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