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Nucleus size and DNA accessibility are linked to the regulation of paraspeckle formation in cellular differentiation

BACKGROUND: Many long noncoding RNAs (lncRNAs) have been implicated in general and cell type-specific molecular regulation. Here, we asked what underlies the fundamental basis for the seemingly random appearance of nuclear lncRNA condensates in cells, and we sought compounds that can promote the dis...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:BMC Biol
Päätekijät: Grosch, Markus, Ittermann, Sebastian, Rusha, Ejona, Greisle, Tobias, Ori, Chaido, Truong, Dong-Jiunn Jeffery, O’Neill, Adam C., Pertek, Anna, Westmeyer, Gil Gregor, Drukker, Micha
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7178590/
https://ncbi.nlm.nih.gov/pubmed/32321486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-020-00770-y
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