Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition

RNA-binding proteins (RBPs) and long non-coding RNAs (lncRNAs) are key regulators of gene expression, but their joint functions in coordinating cell fate decisions are poorly understood. Here we show that the expression and activity of the RBP TDP-43 and the long isoform of the lncRNA Neat1, the sca...

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Publicado no:Mol Cell
Main Authors: Modic, Miha, Grosch, Markus, Rot, Gregor, Schirge, Silvia, Lepko, Tjasa, Yamazaki, Tomohiro, Lee, Flora C.Y., Rusha, Ejona, Shaposhnikov, Dmitry, Palo, Michael, Merl-Pham, Juliane, Cacchiarelli, Davide, Rogelj, Boris, Hauck, Stefanie M., von Mering, Christian, Meissner, Alexander, Lickert, Heiko, Hirose, Tetsuro, Ule, Jernej, Drukker, Micha
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561722/
https://ncbi.nlm.nih.gov/pubmed/31047794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.03.041
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