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Synaptic Depotentiation and mGluR5 Activity in the Nucleus Accumbens Drive Cocaine-Primed Reinstatement of Place Preference

Understanding the neurobiological processes that incite drug craving and drive relapse has the potential to help target efforts to treat addiction. The NAc serves as a critical substrate for reward and motivated behavior, in part due to alterations in excitatory synaptic strength within cortical-acc...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Benneyworth, Michael A., Hearing, Matthew C., Asp, Anders J., Madayag, Aric, Ingebretson, Anna E., Schmidt, Clare E., Silvis, Keelia A., Larson, Erin B., Ebner, Stephanie R., Thomas, Mark J.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561685/
https://ncbi.nlm.nih.gov/pubmed/30948476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3020-17.2019
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