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Aberrant expression of select piRNA-pathway genes does not reactivate piRNA silencing in cancer cells

Germline genes that are aberrantly expressed in nongermline cancer cells have the potential to be ideal targets for diagnosis and therapy due to their restricted physiological expression, their broad reactivation in various cancer types, and their immunogenic properties. Among such cancer/testis gen...

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Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Genzor, Pavol, Cordts, Seth C., Bokil, Neha V., Haase, Astrid D.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561285/
https://ncbi.nlm.nih.gov/pubmed/31110013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904498116
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