Protective role for the N-terminal domain of α-dystroglycan in Influenza A virus proliferation

α-Dystroglycan (α-DG) is a highly glycosylated basement membrane receptor that is cleaved by the proprotein convertase furin, which releases its N-terminal domain (α-DGN). Before cleavage, α-DGN interacts with the glycosyltransferase LARGE1 and initiates functional O-glycosylation of the mucin-like...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: de Greef, Jessica C., Slütter, Bram, Anderson, Mary E., Hamlyn, Rebecca, O’Campo Landa, Raul, McNutt, Ellison J., Hara, Yuji, Pewe, Lecia L., Venzke, David, Matsumura, Kiichiro, Saito, Fumiaki, Harty, John T., Campbell, Kevin P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561248/
https://ncbi.nlm.nih.gov/pubmed/31097590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904493116
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