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Functional cooperation of α-synuclein and VAMP2 in synaptic vesicle recycling
The function of α-synuclein (α-syn) has been long debated, and two seemingly divergent views have emerged. In one, α-syn binds to VAMP2, acting as a SNARE chaperone—but with no effect on neurotransmission—while another posits that α-syn attenuates neurotransmitter release by restricting synaptic ves...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6561242/ https://ncbi.nlm.nih.gov/pubmed/31110017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1903049116 |
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