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Acute increase of α-synuclein inhibits synaptic vesicle recycling evoked during intense stimulation
Parkinson's disease is associated with multiplication of the α-synuclein gene and abnormal accumulation of the protein. In animal models, α-synuclein overexpression broadly impairs synaptic vesicle trafficking. However, the exact steps of the vesicle trafficking pathway affected by excess α-syn...
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| Veröffentlicht in: | Mol Biol Cell |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Cell Biology
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4244201/ https://ncbi.nlm.nih.gov/pubmed/25273557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-02-0708 |
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