α-Synuclein Dimers Impair Vesicle Fission during Clathrin-Mediated Synaptic Vesicle Recycling

α-Synuclein is a presynaptic protein that regulates synaptic vesicle (SV) trafficking. In Parkinson’s disease (PD) and several other neurodegenerative disorders, aberrant oligomerization and aggregation of α-synuclein lead to synaptic dysfunction and neurotoxicity. Despite evidence that α-synuclein...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Front Cell Neurosci
Hlavní autoři: Medeiros, Audrey T., Soll, Lindsey G., Tessari, Isabella, Bubacco, Luigi, Morgan, Jennifer R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732215/
https://ncbi.nlm.nih.gov/pubmed/29321725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00388
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky