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Acute increase of α-synuclein inhibits synaptic vesicle recycling evoked during intense stimulation

Parkinson's disease is associated with multiplication of the α-synuclein gene and abnormal accumulation of the protein. In animal models, α-synuclein overexpression broadly impairs synaptic vesicle trafficking. However, the exact steps of the vesicle trafficking pathway affected by excess α-syn...

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Bibliografiske detaljer
Udgivet i:Mol Biol Cell
Main Authors: Busch, David J., Oliphint, Paul A., Walsh, Rylie B., Banks, Susan M. L., Woods, Wendy S., George, Julia M., Morgan, Jennifer R.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244201/
https://ncbi.nlm.nih.gov/pubmed/25273557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-02-0708
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