CHD4 is essential for transcriptional repression and lineage progression in B lymphopoiesis

Cell lineage specification is a tightly regulated process that is dependent on appropriate expression of lineage and developmental stage-specific transcriptional programs. Here, we show that Chromodomain Helicase DNA-binding protein 4 (CHD4), a major ATPase/helicase subunit of Nucleosome Remodeling...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Arends, Tessa, Dege, Carissa, Bortnick, Alexandra, Danhorn, Thomas, Knapp, Jennifer R., Jia, Haiqun, Harmacek, Laura, Fleenor, Courtney J., Straign, Desiree, Walton, Kendra, Leach, Sonia M., Feeney, Ann J., Murre, Cornelis, O’Connor, Brian P., Hagman, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561196/
https://ncbi.nlm.nih.gov/pubmed/31085655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1821301116
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