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Activation of Aicda gene transcription by Pax5 in plasmacytoma cells
Activation Induced Deaminase (AID) is an enzyme responsible for somatic hypermutation (SHM) and immunoglobulin heavy chain class switch recombination (CSR). Because AID causes double-stranded breaks in DNA, its expression is highly regulated and is normally restricted to germinal center B cells. Dys...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3844280/ https://ncbi.nlm.nih.gov/pubmed/22956488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12026-012-8357-8 |
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