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Genetic and metabolic hallmarks of clear cell renal cell carcinoma
Clear cell renal cell carcinoma (ccRCC) is a malignancy characterized by deregulated hypoxia-inducible factor signaling, mutation of several key chromatin modifying enzymes, and numerous alterations in cellular metabolism. Pre-clinical studies have historically been limited to cell culture models, h...
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| Publicado no: | Biochim Biophys Acta Rev Cancer |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6561085/ https://ncbi.nlm.nih.gov/pubmed/29959988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbcan.2018.06.003 |
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