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Molecular Genetics of Clear-Cell Renal Cell Carcinoma

Renal cell carcinoma of clear-cell type (ccRCC) is an enigmatic tumor type, characterized by frequent inactivation of the VHL gene (infrequently mutated in other tumor types), responsiveness to angiogenesis inhibitors, and resistance to both chemotherapy and conventional radiation therapy. ccRCC tum...

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Detalhes bibliográficos
Autor principal: Brugarolas, James
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050206/
https://ncbi.nlm.nih.gov/pubmed/24821879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2012.45.2003
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