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Molecular Genetics of Clear-Cell Renal Cell Carcinoma

Renal cell carcinoma of clear-cell type (ccRCC) is an enigmatic tumor type, characterized by frequent inactivation of the VHL gene (infrequently mutated in other tumor types), responsiveness to angiogenesis inhibitors, and resistance to both chemotherapy and conventional radiation therapy. ccRCC tum...

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Hlavní autor: Brugarolas, James
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Clinical Oncology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050206/
https://ncbi.nlm.nih.gov/pubmed/24821879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2012.45.2003
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