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Evidence that Ergosterol Biosynthesis Modulates Activity of the Pdr1 Transcription Factor in Candida glabrata

A crucial limitation in antifungal chemotherapy is the limited number of antifungal drugs currently available. Azole drugs represent the most commonly used chemotherapeutic, and loss of efficacy of these drugs is a major risk factor in successful treatment of a variety of fungal diseases. Candida gl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:mBio
Hauptverfasser: Vu, Bao Gia, Thomas, Grace Heredge, Moye-Rowley, W. Scott
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561024/
https://ncbi.nlm.nih.gov/pubmed/31186322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00934-19
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