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Evidence that Ergosterol Biosynthesis Modulates Activity of the Pdr1 Transcription Factor in Candida glabrata

A crucial limitation in antifungal chemotherapy is the limited number of antifungal drugs currently available. Azole drugs represent the most commonly used chemotherapeutic, and loss of efficacy of these drugs is a major risk factor in successful treatment of a variety of fungal diseases. Candida gl...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Vu, Bao Gia, Thomas, Grace Heredge, Moye-Rowley, W. Scott
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561024/
https://ncbi.nlm.nih.gov/pubmed/31186322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00934-19
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