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Benefits of using genomic insulators flanking transgenes to increase expression and avoid positional effects

For more than 20 years, plant biologists have tried to achieve complete control of transgene expression. Until the techniques to target transgenes to safe harbor sites in the genome become routine, flanking transgenes with genetic insulators, DNA sequences that create independent domains of gene exp...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Pérez-González, Ana, Caro, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6560062/
https://ncbi.nlm.nih.gov/pubmed/31186481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44836-6
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