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Benefits of using genomic insulators flanking transgenes to increase expression and avoid positional effects

For more than 20 years, plant biologists have tried to achieve complete control of transgene expression. Until the techniques to target transgenes to safe harbor sites in the genome become routine, flanking transgenes with genetic insulators, DNA sequences that create independent domains of gene exp...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Pérez-González, Ana, Caro, Elena
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6560062/
https://ncbi.nlm.nih.gov/pubmed/31186481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44836-6
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