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C–H hydroxylation in paralytic shellfish toxin biosynthesis

The remarkable degree of synthetic selectivity found in Nature is exemplified by the biosynthesis of paralytic shellfish toxins such as saxitoxin. The polycyclic core shared by saxitoxin and its relatives is assembled and subsequently elaborated through the installation of hydroxyl groups with exqui...

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Détails bibliographiques
Publié dans:J Am Chem Soc
Auteurs principaux: Lukowski, April L., Ellinwood, Duncan C., Hinze, Meagan E., DeLuca, Ryan J., Du Bois, J., Hall, Sherwood, Narayan, Alison R. H.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558983/
https://ncbi.nlm.nih.gov/pubmed/30192526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b08901
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