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C–H hydroxylation in paralytic shellfish toxin biosynthesis

The remarkable degree of synthetic selectivity found in Nature is exemplified by the biosynthesis of paralytic shellfish toxins such as saxitoxin. The polycyclic core shared by saxitoxin and its relatives is assembled and subsequently elaborated through the installation of hydroxyl groups with exqui...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Lukowski, April L., Ellinwood, Duncan C., Hinze, Meagan E., DeLuca, Ryan J., Du Bois, J., Hall, Sherwood, Narayan, Alison R. H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558983/
https://ncbi.nlm.nih.gov/pubmed/30192526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b08901
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