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Biocatalytic Detoxification of Paralytic Shellfish Toxins
[Image: see text] Small molecules that bind to voltage-gated sodium channels (VGSCs) are promising leads in the treatment of numerous neurodegenerative diseases and pain. Nature is a highly skilled medicinal chemist in this regard, designing potent VGSC ligands capable of binding to and blocking the...
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| Опубликовано в: : | ACS Chem Biol |
|---|---|
| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Chemical
Society
2019
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| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6528162/ https://ncbi.nlm.nih.gov/pubmed/30983320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00123 |
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