Potent anti-tumor efficacy of palbociclib in treatment-naïve H3.3K27M-mutant diffuse intrinsic pontine glioma

BACKGROUND: Diffuse intrinsic pontine glioma (DIPG) is a rare and fatal pediatric brain cancer without cure. Seeking therapeutic strategies is still a major challenge in DIPG research. Previous study has shown that dysregulation of G1/S cell cycle checkpoint was common in DIPG and this dysregulation...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:EBioMedicine
Main Authors: Sun, Yu, Sun, Ye, Yan, Kun, Li, Zhuxuan, Xu, Cheng, Geng, Yibo, Pan, Changcun, Chen, Xin, Zhang, Liwei, Xi, Qiaoran
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2019
Teme:
Research paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558223/
https://ncbi.nlm.nih.gov/pubmed/31060906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.04.043
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki