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Anti–CTLA-4 synergizes with dendritic cell–targeted vaccine to promote IL-3–dependent CD4(+) effector T cell infiltration into murine pancreatic tumors
One successful class of cancer immunotherapies, immune checkpoint inhibitory antibodies, disrupt key pathways that regulate immune checkpoints, such as cytotoxic T lymphocyte–associated protein 4 (CTLA-4). These agents unleash the potency of antigen-experienced T cells that have already been induced...
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| Publicado no: | Ann N Y Acad Sci |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6557673/ https://ncbi.nlm.nih.gov/pubmed/30945313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.14049 |
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