Targeting of the non-mutated tumor antigen HER2/neu to mature dendritic cells induces an integrated immune response that protects against breast cancer in mice

INTRODUCTION: Given their relative simplicity of manufacture and ability to be injected repeatedly, vaccines in a protein format are attractive for breast and other cancers. However, soluble human epidermal growth factor receptor (HER2)/neu protein as a vaccine has not been immunogenic. When protein...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Wang, Bei, Zaidi, Neeha, He, Li-Zhen, Zhang, Li, Kuroiwa, Janelle MY, Keler, Tibor, Steinman, Ralph M
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446373/
https://ncbi.nlm.nih.gov/pubmed/22397502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3135
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