Targeting Leishmania major Antigens to Dendritic Cells In Vivo Induces Protective Immunity

Efficient vaccination against the parasite Leishmania major, the causative agent of human cutaneous leishmaniasis, requires development of type 1 T-helper (Th1) CD4(+) T cell immunity. Because of their unique capacity to initiate and modulate immune responses, dendritic cells (DCs) are attractive ta...

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Bibliographic Details
Main Authors: Matos, Ines, Mizenina, Olga, Lubkin, Ashira, Steinman, Ralph M., Idoyaga, Juliana
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694010/
https://ncbi.nlm.nih.gov/pubmed/23840706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067453
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