Siglec-8 in eosinophilic disorders: receptor expression and targeting using chimeric antibodies

BACKGROUND: Sialic acid–binding immunoglobulin-like lectin (Siglec)-8 is selectively expressed on eosinophils, mast cells and basophils, and, when engaged on eosinophils, can cause cell death. OBJECTIVE: To characterize surface and soluble Siglec-8 levels in normal (ND) and eosinophilic (EO) subject...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Legrand, Fanny, Cao, Yun, Wechsler, Joshua, Zhu, Xiang, Zimmermann, Nives, Rampertaap, Shakuntala, Monsale, Joseph, Romito, Kimberly, Youngblood, Bradford A., Brock, Emily C., Makiya, Michelle, Tomasevic, Nenad, Bebbington, Christopher, Maric, Irina, Metcalfe, Dean D., Bochner, Bruce S., Klion, Amy D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556424/
https://ncbi.nlm.nih.gov/pubmed/30543818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2018.10.066
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados