Yüklüyor......

Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST

A truncating mutation in the mouse Srrm4 gene, which encodes a neuronal splicing factor, causes alternative splicing defects selectively in the ear. The mechanism by which splicing is preserved in the brain of these mice is not known. Here, we show that SRRM3 limits the Srrm4 mutation-associated def...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell Rep
Asıl Yazarlar: Nakano, Yoko, Wiechert, Susan, Bánfi, Botond
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556397/
https://ncbi.nlm.nih.gov/pubmed/30995482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.03.072
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!