Differential NOVA2-mediated splicing in excitatory and inhibitory neurons regulates cortical development and cerebellar function

RNA-binding proteins (RBPs) regulate genetic diversity, but the degree to which they do so in individual cell-types in vivo is unknown. We developed NOVA2 cTag-CLIP to generate functional RBP-RNA maps from different neuronal populations in the mouse brain. Combining cell-type datasets from Nova2-cTa...

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Bibliografiske detaljer
Udgivet i:Neuron
Main Authors: Saito, Yuhki, Yuan, Yuan, Zucker-Scharff, Ilana, Fak, John J., Jereb, Saša, Tajima, Yoko, Licatalosi, Donny D., Darnell, Robert B.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6649687/
https://ncbi.nlm.nih.gov/pubmed/30638744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.12.019
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