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Differential NOVA2-mediated splicing in excitatory and inhibitory neurons regulates cortical development and cerebellar function
RNA-binding proteins (RBPs) regulate genetic diversity, but the degree to which they do so in individual cell-types in vivo is unknown. We developed NOVA2 cTag-CLIP to generate functional RBP-RNA maps from different neuronal populations in the mouse brain. Combining cell-type datasets from Nova2-cTa...
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Publicado no: | Neuron |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2019
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6649687/ https://ncbi.nlm.nih.gov/pubmed/30638744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.12.019 |
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