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Second-generation aryl isonitrile compounds targeting multidrug-resistant Staphylococcus aureus
Antibiotic resistance remains a major global public health threat that requires sustained discovery of novel antibacterial agents with unexploited scaffolds. Structure-activity relationship of the first-generation aryl isonitrile compounds we synthesized led to an initial lead molecule that informed...
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| Udgivet i: | Bioorg Med Chem |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6556061/ https://ncbi.nlm.nih.gov/pubmed/30926310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2019.03.034 |
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