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An aryl isonitrile compound with an improved physicochemical profile that is effective in two mouse models of multidrug-resistant Staphylococcus aureus infection

OBJECTIVES: The aim of the present study was to investigate the antibacterial activity of a synthetic aryl isonitrile compound (35) that was developed as part of a compound library to identify new antibacterial agents effective against methicillin-resistant Staphylococcus aureus (MRSA). METHODS: Com...

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Vydáno v:J Glob Antimicrob Resist
Hlavní autoři: Mohammad, Haroon, Kyei-Baffour, Kwaku, Abutaleb, Nader S., Dai, Mingji, Seleem, Mohamed N.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821587/
https://ncbi.nlm.nih.gov/pubmed/31051286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jgar.2019.04.016
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