Discovery and Characterization of Aryl Isonitriles as A New Class of Compounds versus Methicillin- and Vancomycin-resistant Staphylococcus aureus

Methicillin- and vancomycin-resistant Staphylococcus aureus (MRSA and VRSA) have emerged as a global health concern. A new class of compounds featuring an aryl isonitrile moiety has been discovered that exhibits potent inhibitory activity against several clinically-relevant MRSA and VRSA isolates. S...

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Veröffentlicht in:Eur J Med Chem
Hauptverfasser: Davis, Dexter C., Mohammad, Haroon, Kyei-Baffour, Kwaku, Younis, Waleed, Creemer, Cassidy Noel, Seleem, Mohamed N., Dai, Mingji
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686872/
https://ncbi.nlm.nih.gov/pubmed/26164843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2015.06.031
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