OR26-2 Phosphorylation of Estrogen Receptor Alpha is Required for Mammary Gland Development and MCF-7 Breast Tumor Response to Estradiol and Tamoxifen

Serine-167 (S167) is a major phosphorylation site in estrogen receptor alpha (ERα) and a predictor for endocrine therapy response in breast cancer. We previously showed using stable transfection that mutation of S167 to alanine (S167A) impacted MCF-7 breast cancer cell growth and morphology. Using C...

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Dettagli Bibliografici
Pubblicato in:J Endocr Soc
Autori principali: Emneser, Waleed, Anbalagan, Murali, Gomes, Angela, Machado, Heather, Shindo, Sawako, Tian, Dawei, Gao, Y, Chen, H, Subing, Cao, Dong, Yan, Divagaran, Adhira, Rowan, Brian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2019
Soggetti:
Steroid Hormones and Receptors
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554848/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-OR26-2
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