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Estradiol and tamoxifen regulate NRF-1 and mitochondrial function in mouse mammary gland and uterus

Nuclear respiratory factor-1 (NRF-1) stimulates the transcription of nuclear-encoded genes that regulate mitochondrial genome transcription and biogenesis. We reported that estradiol (E(2)) and 4-hydroxytamoxifen (4-OHT) stimulate NRF-1 transcription in an estrogen receptor α- and β- (ERα, ERβ) depe...

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Autors principals: Ivanova, Margarita M., Radde, Brandie N., Son, Jieun, Mehta, Fabiola F., Chung, Sang-Hyuk, Klinge, Carolyn M.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772954/
https://ncbi.nlm.nih.gov/pubmed/23892277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JME-13-0051
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