OR08-3 The Role Of Neuronal Plasticity In The Timing Of Puberty Onset: Insights From A Mkrn3 Deficient Mouse Model.

Makorin ring finger protein 3 (MKRN3) was identified as a regulator of puberty initiation with the report of loss-of-function mutations in association with central precocious puberty (CPP). MKRN3 is a maternally imprinted gene located on chromosome 15q11.2 in humans. In juvenile mice, Mkrn3 is highl...

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Publicat a:J Endocr Soc
Autors principals: Naule, Lydie, Abreu, Ana Paula, Gassaway, Brandon, Kim, Han Kyeol, Liang, Joy, Carroll, Rona, Gygi, Steven, Kaiser, Ursula
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2019
Matèries:
Reproductive Endocrinology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554802/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-OR08-3
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